diminishes the nutrient composition and increases the amount of AGEs in the food: See Malene W. Poulsen, et al., “Advanced Glycation Endproducts in Food and Their Effects on Health,” Food and Chemical Technology 60 (October 2013): 10–37.
Chapter 9
Personalized Meals as Medicine: Pet Food Homework and Fresher Percentages for a Durable Dog
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diminishes the nutrient composition and increases the amount of AGEs in the food: See Malene W. Poulsen, et al., “Advanced Glycation Endproducts in Food and Their Effects on Health,” Food and Chemical Technology 60 (October 2013): 10–37.
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fresher foods are more digestible and assimilative: See Patrícia M. Oba, Pamela L. Utterback, Carl M. Parsons, and Kelly S. Swanson, “True Nutrient and Amino Acid Digestibility of Dog Foods Made with Human-grade Ingredients Using the Precision-fed Cecectomized Rooster Assay,” Translational Animal Science 4, no. 1 (January 2020): 442–51.
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dogs are evolutionarily adapted to deal with a much heavier bacterial load: See Dr. Lea Stogdale’s Letter to the Editor, “Just How Pathogenic to Pets and Humans Are the Bacteria in the Concentrations Found in Raw Pet Foods,” Can Vet J 46 (November 2005): 967.
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their hyper-acidic stomach expertly manages incoming microbes: See Kazuko Sagawa Fasheng Li, Ryan Liese, and Steven C. Sutton, “Fed and Fasted Gastric pH and Gastric Residence Time in Conscious Beagle Dogs,” Journal of Pharmaceutical Sciences 98, no. 7 (July 2009): 2494–2500.
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Also see A. A. Alm-Eldeen, M. H. Mona, A. A. Shati, and H. I. El-Mekkawy, “Synergistic Effect of Black Tea and Curcumin in Improving the Hepatotoxicity Induced by Aflatoxin B1 in Rats,” Toxicol Ind Health 31, no. 12 (December 2015): 1269–80. doi: 10.1177/0748233713491807. Epub 2013 Jun 24. PMID: 23796760.
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just fine when mixed together, just like us: See E. Jean Harper, “Changing Perspectives on Aging and Energy Requirements: Aging and Digestive Function in Humans, Dogs and Cats,” Journal of Nutrition 128, no. 12 (December 1998): 2632S–2635S.
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Dr. Mattson’s lab at the National Institute of Aging has confirmed these findings: To access Dr. Mattson’s comprehensive list of studies, go to his site at https://neuroscience.jhu.edu/research/faculty/57. Also see his review article noted previously.
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Vets regularly recommend fasting for certain dog illnesses: See Lei Sun, et al., “Effect of Fasting Therapy in Chemotherapy-protection and Tumor-suppression: A Systematic Review,” Translational Cancer Research 6, no. 2 (April 2017).
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metabolic syndrome and has been successfully duplicated in animal models: See Amandine Chaix, et al., “Time-Restricted Feeding Prevents Obesity and Metabolic Syndrome in Mice Lacking a Circadian Clock,” Cell Metab 29, no. 2 (February 2019): 303–19.e4. doi: 10.1016/j.cmet.2018.08.004. Epub 2018 Aug 30.

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